Vinpocetine

Vinpocetine is a periwinkle plant extract (Vinca major) that improves brain function. It has been used medicinally in Europe since 1983.

Vinpocetine improves cerebral circulation by dilating the arteries of the brain but does not dilate other blood vessels..

Vinpocetine can prevent the occurrence of stroke. Vinpocetine can prevent much of the damage that occurs following stroke if administered immediately following stroke.
                 
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Vinpocetine:

  • dilates the arteries of the brain but does not dilate other blood vessels

  • improves the brain's utilization of glucose.

  • improves the brain's utilization of oxygen

  • accelerates the rate of learning in animal studies by up to 40%.

  • increases the length of time that short-term memory is retained.  

  • improves circulation to the eyes thereby improving vision and eyesight disorders.

  • improves impaired hearing and improves inner-ear problems.

  • improves Tinnitus (ringing in the ears) and Vertigo (dizziness).

  • can prevent stroke and mitigate damage in the aftermath of stroke.

  • can block the action of drugs that disrupt memory.

  • improved the vertigo (dizziness) of 77% of the patients in one study.

  • improves the flexibility of red blood cells and may thereby help to prevent strokes.

References

Kiss B, Karpati E, Mechanism of action of vinpocetine, Acta Pharm Hung 1996 Sep;66(5):213-24

Feigin VL, et al. Vinpocetine treatment in acute ischaemic stroke a pilot single-blind randomized clinical trial. Eur J Neurol. 2001 Jan;8(1)81-5.

Bonoczk P, et al. Role of sodium channel inhibition in neuroprotection: effect of vinpocetine. Brain Res Bull 2000 Oct;53(3):245-54.

Szakall S, et al. Cerebral effects of a single dose of intravenous vinpocetine in chronic stroke patients: a PET study. J Neuroimaging 1998 Oct;8(4):197-204

A. Szobor and M. Klein (1976) "Vinpocetine therapy in neurovascular disease" Arzneim Forsch (drug research) 28, 1984-89.


F. Solti et al (1976) "Effect of vinpocetine on the cerebral circulation" Arzneim Forsch (drug research) 28, 1945-47.

A. Kaham & M. Olah (1976) "Use of vinpocetine in ophthalmological therapy" Arzneim Forsch (drug research) 28, 1969-72.

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